The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2019
Filed:
Jun. 17, 2016
Applicant:
Astellas Pharma Inc., Chuo-ku, JP;
Inventors:
Shimpei Kawakami, Tokyo, JP;
Tomoyoshi Imaizumi, Tokyo, JP;
Naoyuki Masuda, Tokyo, JP;
Shigeki Kunikawa, Tokyo, JP;
Masataka Morita, Tokyo, JP;
Junko Yarimizu, Tokyo, JP;
Assignee:
Astellas Pharma Inc., Chuo-ku, JP;
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/00 (2006.01); A61K 31/551 (2006.01); A61K 31/5517 (2006.01); C07D 487/04 (2006.01); A61P 25/28 (2006.01); A61P 25/30 (2006.01); A61P 25/18 (2006.01); A61P 25/24 (2006.01); A61P 25/16 (2006.01);
U.S. Cl.
CPC ...
A61K 31/551 (2013.01); A61P 25/16 (2018.01); A61P 25/18 (2018.01); A61P 25/24 (2018.01); A61P 25/28 (2018.01); A61P 25/30 (2018.01); C07D 487/04 (2013.01);
Abstract
Compounds of formula (I) defined herein are useful as a dopamine D1 receptor positive allosteric modulators (D1 PAM) and can be used as an active ingredient of a pharmaceutical composition for preventing and/or treating cognitive impairment, schizophrenia negative symptom, CIAS, Parkinson's disease, Alzheimer's disease, Huntington's disease, depression, ADHD, drug dependency, or the like.