The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 01, 2019

Filed:

May. 29, 2015
Applicants:

Whitehead Institute for Biomedical Research, Cambridge, MA (US);

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

David M. Sabatini, Cambridge, MA (US);

Omer Yilmaz, Ann Arbor, MI (US);

Maria Mihaylova, Somerville, MA (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/426 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/426 (2013.01); A61K 45/06 (2013.01);
Abstract

Disclosed herein are novel methods and compositions useful for promoting intestinal stem cell function. The methods and compositions are particularly useful for stimulating the proliferation of and/or self-renewal of intestinal stem cells, as well as for minimizing, preventing, or ameliorating cellular damage resulting from incidental or accidental exposure to radiation (e.g., cancer radiation therapy).


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