The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10426745 B1

PDF
Full Text
Expired
Date of Patent:
Oct. 01, 2019

Filed:

Mar. 04, 2016
Applicant:

The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);

Inventors:

Leaf Huang, Durham, NC (US);

Yi Zhao, Chapel Hill, NC (US);

Shutao Guo, Jamaica Plain, MA (US);

Kai Shi, Chapel Hill, NC (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 31/155 (2006.01); A61K 47/28 (2006.01); A61K 47/55 (2017.01); A61K 47/61 (2017.01); A61K 47/54 (2017.01); A61K 47/69 (2017.01); A61K 9/51 (2006.01); A61K 9/00 (2006.01); C08G 73/02 (2006.01); C12N 15/85 (2006.01); C12N 15/88 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 31/155 (2013.01); A61K 9/0019 (2013.01); A61K 9/5123 (2013.01); A61K 47/28 (2013.01); A61K 47/55 (2017.08); A61K 47/554 (2017.08); A61K 47/61 (2017.08); A61K 47/6911 (2017.08); A61K 48/00 (2013.01); C08G 73/02 (2013.01); C12N 15/85 (2013.01); C12N 15/88 (2013.01); B82Y 5/00 (2013.01);
Abstract

Provided herein are polymers comprising Metformin residues ('PolyMet') as useful therapeutic agents, delivery vehicles and transfection agents for nucleotides. Also provided herein are methods for the treatment of a disease or an unwanted condition in a subject, wherein the methods comprise administering PolyMet as a therapeutic agent to combat the disease or condition. Also provided herein are methods for the treatment of a disease or an unwanted condition in a subject, wherein the methods comprise administering a therapeutic agent in a delivery vehicle that comprises PolyMet. Further provided herein are methods for making PolyMet.


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