The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2019
Filed:
Aug. 23, 2016
Applicant:
Orbis Biosciences, Inc., Lenexa, KS (US);
Inventors:
Cory Berkland, Lawrence, KS (US);
Milind Singh, Mission, KS (US);
Assignee:
ORBIS BIOSCIENCES, INC., Lenexa, KS (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 9/00 (2006.01); A61K 31/426 (2006.01); A61K 31/573 (2006.01); A61K 47/10 (2017.01);
U.S. Cl.
CPC ...
A61K 9/5026 (2013.01); A61K 9/0053 (2013.01); A61K 9/5015 (2013.01); A61K 9/5063 (2013.01); A61K 9/5089 (2013.01); A61K 31/426 (2013.01); A61K 31/573 (2013.01); A61K 47/10 (2013.01);
Abstract
The present disclosure relates to a taste-masking microcapsule composition. The composition comprises a core portion encapsulated by a shell portion. The core portion comprises an active pharmaceutical ingredient (API) and one or more excipients. The shell portion comprises a hydrophobic matrix and a pH-responsive material. The microcapsule compositions prevent API release at the more neutral pH levels in the oral cavity, but upon exposure to pH levels of the stomach, the pH-responsive material becomes soluble thereby permitting release of the API.