The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2019
Filed:
Feb. 19, 2019
Applicant:
Tolero Pharmaceuticals, Inc., Lehi, UT (US);
Inventors:
David J. Bearss, Alpine, UT (US);
Adam Siddiqui-Jain, South Jordan, UT (US);
Clifford J. Whatcott, West Jordan, UT (US);
Peter W. Peterson, Salt Lake City, UT (US);
Steven L. Warner, Sandy, UT (US);
Lars Mouritsen, Lehi, UT (US);
Assignee:
TOLERO PHARMACEUTICALS, INC., Lehi, UT (US);
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); G01N 33/50 (2006.01); A61P 35/02 (2006.01); A61K 31/704 (2006.01); A61K 31/496 (2006.01); A61K 31/136 (2006.01); A61K 31/7068 (2006.01); A61K 31/4545 (2006.01); C07K 14/47 (2006.01); C12Q 1/6886 (2018.01); A61K 45/06 (2006.01); C12N 7/00 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5091 (2013.01); A61K 31/136 (2013.01); A61K 31/4545 (2013.01); A61K 31/496 (2013.01); A61K 31/704 (2013.01); A61K 31/7068 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01); C07K 14/00 (2013.01); C07K 14/4747 (2013.01); C12N 7/00 (2013.01); C12Q 1/6886 (2013.01); G01N 33/5011 (2013.01); G01N 33/5079 (2013.01); C07K 2319/10 (2013.01); C12N 2740/16322 (2013.01); G01N 2333/47 (2013.01); G01N 2800/56 (2013.01);
Abstract
The present disclosure is generally directed to profiling peptides, compositions, and kits, as well as methods of use thereof. The profiling peptides comprise an Mcl-1 binding domain, and optionally a cellular uptake moiety. The methods of using such profiling peptides include predicting sensitivity of a cancer, selecting a treatment, treating a cancer, producing a sensitivity profile, and the like.