The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 24, 2019

Filed:

Feb. 15, 2017
Applicant:

Quark Pharmaceuticals Inc., Fremont, CA (US);

Inventors:

Elena Feinstein, Rehovot, IL;

Sharon Avkin-Nachum, Nes Zionna, IL;

Hagar Kalinski, Rishon le Zion, IL;

Igor Mett, Rehovot, IL;

Assignee:

Quark Pharmaceuticals, Inc., Newark, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12N 15/1135 (2013.01); C12N 15/1136 (2013.01); C12N 2310/14 (2013.01); C12N 2310/317 (2013.01); C12N 2310/319 (2013.01); C12N 2310/321 (2013.01); C12N 2310/3521 (2013.01); C12N 2320/30 (2013.01);
Abstract

Provided herein are double stranded nucleic acid molecules, compositions comprising same and methods of use thereof for the treatment of a subject wherein expression of DDIT4 is associated with the etiology or progression of a disease or disorder in the subject. The compounds are preferably chemically synthesized and modified dsRNA molecules.


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