The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2019
Filed:
Jan. 22, 2019
Applicant:
Beijing Mabworks Biotech Co.ltd, Beijing, CN;
Inventors:
Wenqi Hu, Las Vegas, NV (US);
Jiangmei Li, Beijing, CN;
Xia Wang, Beijing, CN;
Feng Li, Beijing, CN;
Assignee:
BEIJING MABWORKS BIOTECH CO., LTD., Beijing, CN;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 47/68 (2017.01); A61K 31/704 (2006.01); A61K 31/7115 (2006.01); A61K 31/282 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); A61K 31/282 (2013.01); A61K 31/704 (2013.01); A61K 31/7115 (2013.01); A61K 47/6801 (2017.08);
Abstract
An isolated monoclonal antibody that specifically binds human Claudin 18.2. A nucleic acid molecule encoding the antibody, an expression vector, a host cell and a method for expressing the antibody are also provided. The present invention further provides an immunoconjugate, a bispecific molecule, a chimeric antigen receptor, an oncolytic virus and a pharmaceutical composition comprising the antibody, as well as a diagnostic or treatment method using an anti-Claudin 18.2 antibody of the invention.