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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10421812 B1

PDFFull Text
Date of Patent:
Sep. 24, 2019

Filed:

Mar. 31, 2016

Isoform specific soluble fms-like tyrosine kinase (sflt) binding agents and uses thereof

Applicant:

University of Massachusetts, Boston, MA (US);

Inventors:

Teresa Broering, Brookline, MA (US);

Colby Souders, North Weymouth, MA (US);

Gregory Babcock, Marlborough, MA (US);

Naomi Boatright, Quincy, MA (US);

Assignee:

University of Massachusetts, Boston, MA (US);

Attorney:

Wolf, Greenfield & Sacks, P.C.

Primary Examiner:

Bao Thuy L Nguyen

Assistant Examiner:

Ellen J Marcsisin

Int. Cl.
CPC ...
C07K 16/28 (2006.01); G01N 33/68 (2006.01); C07K 16/40 (2006.01); C07H 1/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2863 (2013.01); C07H 1/00 (2013.01); C07K 16/40 (2013.01); G01N 33/689 (2013.01); C07K 2317/21 (2013.01); C07K 2317/92 (2013.01); G01N 2333/71 (2013.01); G01N 2800/368 (2013.01);
Abstract

Aspects of the present disclosure relate to binding agents (e.g., antibodies and antigen binding fragments) that bind soluble fms-like tyrosine kinase 1 (sFlt1) in an isoform specific manner. In some embodiments, immunological assay methods utilizing isoform-specific antibodies or antigen binding fragments that bind sFlt1 isoforms are provided for assessing biological samples obtained from pregnant subjects, e.g., for purposes of evaluating preeclampsia status in the subject.

Find Patent Forward Citations

Broering, Teresa. (2019). Isoform specific soluble fms-like tyrosine kinase (sflt) binding agents and uses thereof (U.S. Patent No. 10421812). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10421812

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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