The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 24, 2019

Filed:

Oct. 16, 2014
Applicants:

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);

Versitech Limited, Hong Kong, HK;

Inventors:

Dimiter S. Dimitrov, Frederick, MD (US);

Tianlei Ying, Frederick, MD (US);

Tina W. Ju, Ashburn, VA (US);

Kwok Yung Yuen, Hong Kong, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/10 (2006.01); A61K 39/42 (2006.01); A61K 45/06 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
C07K 16/10 (2013.01); A61K 39/42 (2013.01); A61K 45/06 (2013.01); C07K 14/005 (2013.01); C12N 7/00 (2013.01); G01N 33/56983 (2013.01); C07K 2317/21 (2013.01); C07K 2317/31 (2013.01); C07K 2317/526 (2013.01); C07K 2317/55 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2319/00 (2013.01); C07K 2319/70 (2013.01); C12N 2770/20033 (2013.01); G01N 2333/165 (2013.01); G01N 2469/10 (2013.01);
Abstract

The invention provides polypeptides (e.g., antibodies) and fusion proteins that target a epitope in the receptor binding domain (RBD) of the spike (S) glycoprotein of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV). The polypeptides and fusion proteins can be used to treat and prevent MERS-CoV infection in mammals.


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