The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 24, 2019

Filed:

Jun. 19, 2018
Applicant:

Emory University, Atlanta, GA (US);

Inventors:

Michael Davis, Atlanta, GA (US);

Mario Martinez, Atlanta, GA (US);

Assignees:

Emory University, Atlanta, GA (US);

Children's Healthcare of Atlanta, Inc., Atlanta, GA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); A61K 47/54 (2017.01); A61K 47/60 (2017.01); A61K 49/18 (2006.01); A61K 49/14 (2006.01); A61K 47/64 (2017.01); A61K 49/00 (2006.01); C07K 17/14 (2006.01); G01N 33/58 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61K 47/542 (2017.08); A61K 47/60 (2017.08); A61K 47/64 (2017.08); A61K 49/0032 (2013.01); A61K 49/0056 (2013.01); A61K 49/14 (2013.01); A61K 49/1821 (2013.01); C07K 17/14 (2013.01); G01N 33/582 (2013.01); A61K 38/00 (2013.01); G01N 2800/32 (2013.01);
Abstract

This disclosure relates to peptides useful for targeting inflamed or distressed tissue and uses related thereto. In certain embodiment, the peptides comprise SEQ ID NO: 1-14, or variants or derivatives thereof. In certain embodiments, peptides disclosed herein are conjugated to a label to detect, measure, or image cardiac tissue useful in the diagnosis of myocarditis. In certain embodiments, the peptides are conjugated to a particle coating for use in ultrasound imaging, MRI, or targeted therapy. In certain embodiments, peptides disclosed herein are conjugated to a drug or a particle containing a drug useful for targeted therapy.


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