The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 24, 2019

Filed:

Aug. 25, 2017
Applicant:

Kyungpook National University Industry-academic Cooperation Foundation, Daegu, KR;

Inventors:

Byung-Heon Lee, Daegu, KR;

Bodhraj Acharya, Daegu, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/436 (2006.01); A61K 47/50 (2017.01); A61K 47/62 (2017.01); A61K 49/00 (2006.01); C07K 19/00 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); G01N 33/58 (2006.01); A61K 31/4706 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
C07K 7/06 (2013.01); A61K 31/436 (2013.01); A61K 31/4706 (2013.01); A61K 47/50 (2017.08); A61K 47/62 (2017.08); A61K 49/00 (2013.01); G01N 33/56966 (2013.01); G01N 33/58 (2013.01); C07K 2319/035 (2013.01);
Abstract

An autophagic cell targeted peptide and its use are described. More particularly, a polypeptide comprising an amino acid sequence represented by the general formula (I) and specifically binding to an autophagic cell and a composition for detecting autophagic cells comprising the same as an active ingredient are described. Also described are a drug delivery composition containing the same peptide as an active ingredient and a composition for imaging comprising the same peptide as an active ingredient. The peptide specifically binds to the cell membrane of autophagic cells and can be applied to various kinds of tissues and cells. The detection and imaging effect of autophagy is remarkable in vitro and in vivo.


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