The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2019
Filed:
Jun. 09, 2017
Applicant:
Gilead Sciences, Inc., Foster City, CA (US);
Inventors:
Peter A. Blomgren, Issaquah, WA (US);
Kevin S. Currie, North Bend, WA (US);
Christian Gege, Mauer, DE;
Jeffrey E. Kropf, Issaquah, WA (US);
Jianjun Xu, Seattle, WA (US);
Assignee:
Gilead Sciences, Inc., Foster City, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 261/10 (2006.01); C07D 205/02 (2006.01); C07C 13/04 (2006.01); C07C 25/13 (2006.01); C07C 39/28 (2006.01); A61K 31/42 (2006.01); A61K 31/44 (2006.01); C07D 401/14 (2006.01); C07D 413/14 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
C07D 261/10 (2013.01); A61K 31/42 (2013.01); A61K 31/44 (2013.01); C07C 13/04 (2013.01); C07C 25/13 (2013.01); C07C 39/28 (2013.01); C07D 205/02 (2013.01); C07D 401/14 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01);
Abstract
The present disclosure relates generally to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.