The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2019
Filed:
Dec. 17, 2015
Applicant:
California Institute of Technology, Pasadena, CA (US);
Inventors:
Brian M. Stoltz, San Marino, CA (US);
Yoshitaka Numajiri, Kamakura, JP;
Beau P. Pritchett, Pasadena, CA (US);
Koji Chiyoda, Gotenba, JP;
Assignee:
California Institute of Technology, Pasadena, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07B 53/00 (2006.01); C07D 209/88 (2006.01); C07D 211/74 (2006.01); C07D 211/76 (2006.01); C07D 265/32 (2006.01); C07C 271/18 (2006.01); C07C 271/50 (2006.01); C07C 311/16 (2006.01); C07C 233/76 (2006.01);
U.S. Cl.
CPC ...
C07B 53/00 (2013.01); C07C 233/76 (2013.01); C07C 271/18 (2013.01); C07C 271/50 (2013.01); C07C 311/16 (2013.01); C07D 209/88 (2013.01); C07D 211/74 (2013.01); C07D 211/76 (2013.01); C07D 265/32 (2013.01); C07B 2200/07 (2013.01); C07C 2601/08 (2017.05); C07C 2601/14 (2017.05); C07C 2601/18 (2017.05); C07C 2602/10 (2017.05);
Abstract
This invention provides enantioenriched Mannich adducts with quaternary stereogenic centers and novel methods of preparing the compounds. Methods include the method for the preparation of a compound of formula (I): comprising treating a compound of formula (II): with a transition metal catalyst under alkylation conditions.