The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2019
Filed:
Jun. 16, 2016
Applicant:
Ramot AT Tel-aviv University Ltd., Tel Aviv, IL;
Inventors:
Doron Shabat, Tel Aviv, IL;
Ronit Satchi-Fainaro, Tel Aviv, IL;
Samer Gnaim, Baqa El-Garbia, IL;
Anna Scomparin, Tel Aviv, IL;
Assignee:
Ramot at Tel-Aviv University Ltd., Tel Aviv, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/22 (2006.01); A61K 47/54 (2017.01); A61K 31/436 (2006.01); A61K 31/4188 (2006.01); A61K 31/497 (2006.01); A61K 31/519 (2006.01); C07D 487/04 (2006.01); C07D 215/44 (2006.01); A61P 35/00 (2006.01); A61K 31/4184 (2006.01); A61K 31/4745 (2006.01); A61K 31/496 (2006.01); A61K 31/513 (2006.01);
U.S. Cl.
CPC ...
A61K 47/555 (2017.08); A61K 31/4184 (2013.01); A61K 31/4188 (2013.01); A61K 31/436 (2013.01); A61K 31/4745 (2013.01); A61K 31/496 (2013.01); A61K 31/497 (2013.01); A61K 31/513 (2013.01); A61K 31/519 (2013.01); A61K 47/54 (2017.08); A61P 35/00 (2018.01); C07D 215/44 (2013.01); C07D 487/04 (2013.01); C07D 491/22 (2013.01);
Abstract
The present disclosure provides heteroarene-based drug derivatives having a 'clickable' ketone group, as well as conjugates of said drug derivatives with targeting moieties capable of binding to extracellular antigens; and pharmaceutical compositions comprising them.