The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 24, 2019

Filed:

Apr. 13, 2014
Applicant:

Bar-ilan University, Ramat Gan, IL;

Inventors:

Ido Bachelet, Modiin, IL;

Almogit Abu-Horowitz, Hertzeliya, IL;

Eldad Ben-Ishay, Shoham, IL;

Yaniv Amir, Yehud, IL;

Ariel Munitz, Jerusalem, IL;

Anastasia Shapiro, Rishon Lezion, IL;

Amir Shemer, Petach Tikva, IL;

Zeev Zalevsky, Rosh HaAyin, IL;

Assignee:

BAR-ILAN UNIVERSITY, Ramat Gan, IL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/115 (2010.01); A61K 47/48 (2006.01); C12Q 1/68 (2018.01); A61K 38/28 (2006.01); A61K 47/54 (2017.01); A61K 47/69 (2017.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 47/48776 (2013.01); A61K 38/28 (2013.01); A61K 47/549 (2017.08); A61K 47/6901 (2017.08); A61K 47/6923 (2017.08); C12N 15/115 (2013.01); C12Q 1/68 (2013.01); B82Y 5/00 (2013.01); C12N 2310/16 (2013.01); C12N 2310/351 (2013.01); C12N 2310/3519 (2013.01); C12N 2310/3521 (2013.01); C12N 2310/51 (2013.01); C12N 2320/51 (2013.01); C12N 2320/53 (2013.01); C12N 2730/10151 (2013.01);
Abstract

Nucleic acid origami devices are provided that are non-immunogenic and/or resistant to nucleases, which may be activated by one or more external cues, such as ligands, glucose concentration or electromagnetic fields; or used for attenuation or prevention of internalization of cell-surface receptors or prolongation of shelf-life of active agents. Further provided are methods for treating diabetes and methods for preparing the devices.


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