The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2019
Filed:
Mar. 13, 2013
Dana-farber Cancer Institute, Inc., Boston, MA (US);
The General Hospital Corporation, Boston, MA (US);
Anne Fletcher, Oakleigh South, AU;
Shannon J. Turley, West Roxbury, MA (US);
Biju Parekkadan, Cambridge, MA (US);
The General Hospital Corporation, Boston, MA (US);
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Abstract
A method for suppressing an immune response is provided. The method involves administration of isolated lymphoid tissue-derived suppressive stromal cells (LSSC) to a subject in need of such treatment in an amount effective to suppress the immune response in the subject. The invention also involves a method to isolate LSSC by digesting lymphoid tissue fragments using a combination of an enzyme mix and agitation and then collecting the LSSC. Pharmaceutical preparations comprising LSSC are also provided.