The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 24, 2019

Filed:

Mar. 05, 2015
Applicants:

Sph No.1 Biochemical & Pharmaceutical Co., Ltd., Shanghai, CN;

Shanghai Ziyuan Pharmaceutical Co., Ltd., Shanghai, CN;

Inventors:

Zhenhui Huang, Shanghai, CN;

Liuqing Yang, Shanghai, CN;

Jianli Huo, Shanghai, CN;

Xinlei Zhu, Shanghai, CN;

Jinguo Ding, Shanghai, CN;

Zhigang Zhang, Shanghai, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7076 (2006.01); C07H 1/06 (2006.01); C07H 19/213 (2006.01); C07F 9/6574 (2006.01); G01N 21/35 (2014.01); G01N 23/20 (2018.01); G01N 25/48 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7076 (2013.01); C07H 1/06 (2013.01); C07H 19/213 (2013.01); C07B 2200/13 (2013.01); C07F 9/65744 (2013.01); G01N 21/35 (2013.01); G01N 23/20075 (2013.01); G01N 25/4866 (2013.01);
Abstract

Disclosed are a crystallization water-free calcium dibutyryladenosine cyclophosphate crystal form, and a preparation method and a use thereof. In an X-ray powder diffraction pattern using Cu-Kα as a source of radiation, the crystallization water-free calcium dibutyryladenosine cyclophosphate crystal form has characteristic peaks at positions where diffraction angles 2θ are equal to 12.3°±0.2°, 17.6°±0.2°, 21.4°±0.2°, 24.7°±0.2°, 25.3°±0.2° and 27.8°±0.2°. The crystallization water-free calcium dibutyryladenosine cyclophosphate crystal form of the present invention has a high purity, and good stability; the preparation method is simple and convenient, has good reproducibility, and is easy to industrially popularize and apply.


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