The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 24, 2019

Filed:

Apr. 24, 2018
Applicant:

Rugen Holdings (Cayman) Limited, Grand Cayman, KY;

Inventor:

Gideon Shapiro, Gainesville, FL (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); C07D 487/04 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 9/0053 (2013.01); C07D 487/04 (2013.01);
Abstract

Disclosed are chemical entities of formula I: wherein X, Y, Z, R, R, R, Rand Rare defined herein, as NR2B subtype selective receptor antagonists. Also disclosed are pharmaceutical compositions comprising a chemical entity of formula I, and methods of treating various diseases and disorders associated with NR2B antagonism, e.g., diseases and disorders of the CNS, such as depression, by administering a chemical entity of formula I.


Find Patent Forward Citations

Shapiro, Gideon. (2019). Pyrrolopyrimidine derivatives as nr2b nmda receptor antagonists (U.S. Patent No. 10420768). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10420768

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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