The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2019
Filed:
Jan. 05, 2018
Applicants:
Indiana University Research and Technology Corporation, Indianapolis, IN (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Inventors:
Elliot J. Androphy, Indianapolis, IN (US);
Kevin Hodgetts, Framingham, MA (US);
Alyssa Nicole Calder, Cambridge, MA (US);
Assignee:
Indiana University Research and Technology Corporation, Indianapolis, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/501 (2006.01); A61K 31/50 (2006.01); A61K 31/437 (2006.01); A61K 31/444 (2006.01); A61K 31/4704 (2006.01); A61K 31/506 (2006.01); A61K 45/06 (2006.01); A61K 31/422 (2006.01); A61K 31/426 (2006.01); A61K 31/427 (2006.01); A61K 31/4418 (2006.01); A61K 31/4709 (2006.01); A61K 31/4985 (2006.01); A61K 31/517 (2006.01); A61K 31/7125 (2006.01);
U.S. Cl.
CPC ...
A61K 31/437 (2013.01); A61K 31/422 (2013.01); A61K 31/426 (2013.01); A61K 31/427 (2013.01); A61K 31/444 (2013.01); A61K 31/4418 (2013.01); A61K 31/4704 (2013.01); A61K 31/4709 (2013.01); A61K 31/4985 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/517 (2013.01); A61K 31/7125 (2013.01); A61K 45/06 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0318 (2013.01);
Abstract
Disclosed herein are compositions and methods for treatment of spinal muscular atrophy (SMA). In certain embodiments, compounds are provided that increase full-length survival of motor neuron (SMN) protein production by an SMN2 gene.