The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 24, 2019

Filed:

Feb. 28, 2018
Applicant:

Ligand Pharmaceuticals Incorporated, San Diego, CA (US);

Inventors:

Keith B. Marschke, La Jolla, CA (US);

Lin Zhi, La Jolla, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4045 (2006.01); A61K 31/4152 (2006.01); A61K 45/06 (2006.01); A61K 31/41 (2006.01); A61K 31/4155 (2006.01); A61K 31/454 (2006.01); A61N 5/10 (2006.01); G01N 33/50 (2006.01); A61K 31/40 (2006.01); A61K 31/4015 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4045 (2013.01); A61K 31/41 (2013.01); A61K 31/4152 (2013.01); A61K 31/4155 (2013.01); A61K 31/454 (2013.01); A61K 45/06 (2013.01); A61N 5/10 (2013.01); G01N 33/5011 (2013.01); A61K 31/40 (2013.01); A61K 31/4015 (2013.01);
Abstract

Some embodiments include methods for treating, preventing, reversing, halting, or slowing the progression of cancer, comprising administering to a subject in need thereof an effective amount of one or more chemotherapeutic agents, or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition, wherein at least one of the chemotherapeutic agents is a cytotoxic granulocyte colony-stimulating factor receptor (GCFR) modulator. Methods are also disclosed for treating, preventing, reversing, halting, or slowing the progression of a hematopoietic disorder, comprising administered a therapeutically effective cytotoxic amount of a GCFR modulator to a subject in need thereof.


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