The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2019
Filed:
Sep. 14, 2017
Applicant:
The Children's Medical Center Corporation, Boston, MA (US);
Inventors:
Assignee:
The Children's Medical Center Corporation, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/202 (2006.01); A61K 31/20 (2006.01); A61K 31/192 (2006.01); A61K 31/196 (2006.01); A61K 31/343 (2006.01); A61K 31/201 (2006.01);
U.S. Cl.
CPC ...
A61K 31/202 (2013.01); A61K 31/192 (2013.01); A61K 31/196 (2013.01); A61K 31/20 (2013.01); A61K 31/201 (2013.01); A61K 31/343 (2013.01);
Abstract
Disclosed herein are compositions and methods for treating or preventing certain cancers in a subject. In certain embodiments such compositions and methods generally relate to the use of G-coupled protein receptor 40 (GPR40) agonists to inhibit the growth or induce apoptosis of certain cancer cells. The compositions and related methods disclosed herein may be used to treat subjects affected by cancers, such as melanoma, medullary thyroid carcinoma, malignant peripheral nerve sheath tumors and neuroblastoma, and to reduce the incidence of metastases in such affected subjects.