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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10420741 B1

PDFFull Text
Date of Patent:
Sep. 24, 2019

Filed:

Jul. 21, 2016

Megalin antagonist

Applicants:

Ea Pharma Co., Ltd., Chuo-ku, JP;

Niigata University, Niigata-shi, JP;

Inventors:

Akihiko Saito, Niigata, JP;

Nobumasa Aoki, Niigata, JP;

Yoshihisa Hori, Tokamachi, JP;

Shoji Kuwahara, Niigata, JP;

Michihiro Hosojima, Sanjo, JP;

Hiroshi Iwata, Kawasaki, JP;

Saori Matsuda, Kawasaki, JP;

Assignees:

EA Pharma Co., Ltd., Chuo-ku, JP;

Niigata University, Niigata-shi, JP;

Attorney:

Oblon, McClelland, Maier & Neustadt, L.L.P.

Primary Examiner:

Shawquia Jackson

Int. Cl.
CPC ...
A61K 31/19 (2006.01); A61K 33/24 (2019.01); A61K 31/198 (2006.01); A61K 45/06 (2006.01); A61K 38/12 (2006.01); A61K 38/14 (2006.01); A61K 31/436 (2006.01); B65D 81/32 (2006.01);
U.S. Cl.
CPC ...
A61K 31/198 (2013.01); A61K 31/436 (2013.01); A61K 33/24 (2013.01); A61K 38/12 (2013.01); A61K 38/14 (2013.01); A61K 45/06 (2013.01); B65D 81/32 (2013.01);
Abstract

The present invention includes cilastatin or a pharmaceutically acceptable salt thereof as an active component and a suppressant for renal impairment or inner ear disorders, induced via megalin by at least one megalin ligand which is selected from the group consisting of polymyxins, aminoglycoside antibiotics, glycopeptide antibiotics, cisplatin, and pharmaceutically acceptable salts thereof.

Find Patent Forward Citations

Saito, Akihiko. (2019). Megalin antagonist (U.S. Patent No. 10420741). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10420741

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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