The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2019
Filed:
Jul. 21, 2016
Applicants:
Ea Pharma Co., Ltd., Chuo-ku, JP;
Niigata University, Niigata-shi, JP;
Inventors:
Akihiko Saito, Niigata, JP;
Nobumasa Aoki, Niigata, JP;
Yoshihisa Hori, Tokamachi, JP;
Shoji Kuwahara, Niigata, JP;
Michihiro Hosojima, Sanjo, JP;
Hiroshi Iwata, Kawasaki, JP;
Saori Matsuda, Kawasaki, JP;
Assignees:
EA Pharma Co., Ltd., Chuo-ku, JP;
Niigata University, Niigata-shi, JP;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/19 (2006.01); A61K 33/24 (2019.01); A61K 31/198 (2006.01); A61K 45/06 (2006.01); A61K 38/12 (2006.01); A61K 38/14 (2006.01); A61K 31/436 (2006.01); B65D 81/32 (2006.01);
U.S. Cl.
CPC ...
A61K 31/198 (2013.01); A61K 31/436 (2013.01); A61K 33/24 (2013.01); A61K 38/12 (2013.01); A61K 38/14 (2013.01); A61K 45/06 (2013.01); B65D 81/32 (2013.01);
Abstract
The present invention includes cilastatin or a pharmaceutically acceptable salt thereof as an active component and a suppressant for renal impairment or inner ear disorders, induced via megalin by at least one megalin ligand which is selected from the group consisting of polymyxins, aminoglycoside antibiotics, glycopeptide antibiotics, cisplatin, and pharmaceutically acceptable salts thereof.