The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 24, 2019

Filed:

Sep. 30, 2016
Applicant:

Vium, Inc., San Mateo, CA (US);

Inventors:

Daniel J. Ford, San Francisco, CA (US);

Laura Schaevitz, Los Gatos, CA (US);

Assignee:

Vium, Inc., San Mateo, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 5/11 (2006.01); A01K 29/00 (2006.01); A01K 1/03 (2006.01); A61D 99/00 (2006.01);
U.S. Cl.
CPC ...
A61B 5/4848 (2013.01); A01K 1/031 (2013.01); A01K 29/005 (2013.01); A61B 5/1118 (2013.01); A61B 5/4076 (2013.01); A61B 5/4842 (2013.01); A61B 5/7282 (2013.01); A61B 5/7257 (2013.01); A61B 2503/40 (2013.01); A61B 2503/42 (2013.01); A61D 99/00 (2013.01);
Abstract

A method of measuring efficacy of treatment of multiple sclerosis (MS) in an animal in a vivarium is described. Animal activity data is collected at multiple times during the night. Sequential time regions of the night are identified as high-activity, activity-drop, or low-activity regions. Embodiments are described to quantify a drop, during the night, of an animal's activity level. These quantified activity-drop scalars for consecutive nights are accumulated in an animal health dataset. This dataset is compared to healthy animals or a standard of care to determine efficacy. One embodiment quantifies an activity-drop by fitting straight-line curves through the data in the three nightly regions. Another embodiment uses a Fourier transform on a circle and a linear combination. Another embodiment compares areas under data curves in the regions. Animals may be housed in cages with other animals.


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