The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 24, 2019
Filed:
Jun. 09, 2014
Research Foundation of the City University of New York, New York, NY (US);
Robert R. Alfano, Bronx, NY (US);
Yang Pu, New York, NY (US);
Lingyan Shi, New York, NY (US);
Sebastião Pratavieira, São Paulo, BR;
Research Foundation of the City University of New York, New York, NY (US);
Abstract
A method is provided for deep tissue imaging using multi-photon excitation of a fluorescent agent. The fluorescent agent is irradiated with an ultrafast laser to produce an excited singlet state (S) which subsequently undergoes non-radiative relaxation to a first singlet state (S). The Sstate undergoes fluorescence to the ground state Sto produce an emission wavelength. Both the excitation and emission wavelengths are within the near infrared optical window, thereby permitting deep tissue penetration for both the incoming and outgoing signals.