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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10416161 B1

PDFFull Text
Date of Patent:
Sep. 17, 2019

Filed:

Sep. 20, 2016

Exosome-mediated diagnosis of hepatitis virus infections and diseases

Applicant:

Morehouse School of Medicine, Atlanta, GA (US);

Inventors:

Gale W. Newman, Duluth, GA (US);

Sam Anyanwu, Atlanta, GA (US);

Assignee:

MOREHOUSE SCHOOL OF MEDICINE, Atlanta, GA (US);

Attorneys:

Ping Wang

Morris, Manning & Martin, LLP

Primary Examiner:

M Franco G Salvoza

Int. Cl.
CPC ...
G01N 33/53 (2006.01); C12Q 1/70 (2006.01); A61K 39/42 (2006.01); G01N 33/569 (2006.01); G01N 33/493 (2006.01); G01N 33/68 (2006.01); G01N 33/576 (2006.01); G01N 1/40 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56988 (2013.01); C12Q 1/70 (2013.01); C12Q 1/703 (2013.01); C12Q 1/706 (2013.01); C12Q 1/707 (2013.01); G01N 33/493 (2013.01); G01N 33/56983 (2013.01); G01N 33/576 (2013.01); G01N 33/6893 (2013.01); G01N 1/40 (2013.01); G01N 2333/02 (2013.01); G01N 2333/10 (2013.01); G01N 2333/161 (2013.01); G01N 2333/162 (2013.01); G01N 2333/163 (2013.01); G01N 2333/186 (2013.01); G01N 2800/347 (2013.01); G01N 2800/52 (2013.01); G01N 2800/56 (2013.01); Y02A 50/54 (2018.01);
Abstract

A method for diagnosing hepatitis virus infection or a hepatitis disease condition in a subject based on hepatitis virus-associated biomarkers present on exosomes in a bodily fluid sample from the subject is disclosed. Also disclosed are a method for monitoring the course of a hepatitis virus infection or a hepatitis disease condition in a subject and a method for monitoring effectiveness of treatment to a subject with an anti-hepatitis virus agent based on hepatitis virus-associated biomarkers present on exosomes in bodily fluid samples from the subject, as well as a kit for diagnosing hepatitis virus infection and/or a hepatitis disease condition in a subject based on hepatitis virus-associated biomarkers on exosomes in bodily fluid samples from the subject.

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