The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2019
Filed:
Feb. 10, 2017
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventors:
J. Keith Joung, Winchester, MA (US);
Jeffry D. Sander, Ankeny, IA (US);
Morgan Maeder, Brookline, MA (US);
Yanfang Fu, Malden, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/02 (2006.01); C12N 9/10 (2006.01); C12N 9/16 (2006.01); C12N 9/22 (2006.01); C12N 9/96 (2006.01); C12N 15/01 (2006.01); C12N 15/10 (2006.01); C12N 15/11 (2006.01); C12N 15/63 (2006.01); C12N 15/85 (2006.01); C12N 15/90 (2006.01); C07K 14/005 (2006.01); C07K 14/195 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); C07K 14/005 (2013.01); C07K 14/195 (2013.01); C12N 9/0071 (2013.01); C12N 9/1007 (2013.01); C12N 9/16 (2013.01); C12N 9/22 (2013.01); C12N 9/96 (2013.01); C12N 15/01 (2013.01); C12N 15/102 (2013.01); C12N 15/1031 (2013.01); C12N 15/11 (2013.01); C12N 15/63 (2013.01); C12N 15/85 (2013.01); C12Y 301/21004 (2013.01); C07K 2319/00 (2013.01); C07K 2319/01 (2013.01); C07K 2319/80 (2013.01); C12N 2310/20 (2017.05); C12N 2710/00033 (2013.01); C12N 2770/00033 (2013.01); C12N 2800/80 (2013.01); C12Y 114/11 (2013.01); C12Y 201/01 (2013.01); C12Y 301/00 (2013.01);
Abstract
Methods for increasing specificity of RNA-guided genome editing, e.g., editing using CRISPR/Cas9 systems, using truncated guide RNAs (tru-gRNAs).