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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10415054 B1

PDFFull Text
Date of Patent:
Sep. 17, 2019

Filed:

Feb. 03, 2014

Designer circuit controlling diet-induced obesity

Applicant:

Eth Zurich, Zurich, CH;

Inventors:

Katrin Rossger, Zurich, CH;

Martin Fussenegger, Magenwil, CH;

Assignee:

ETH ZURICH, Zurich, SE;

Attorney:

Medler Ferro Woodhouse & Mills PLLC

Primary Examiner:

James D Schultz

Int. Cl.
CPC ...
C12N 15/85 (2006.01); A61K 35/12 (2015.01); C12N 15/09 (2006.01); A61K 38/10 (2006.01); A61K 38/18 (2006.01); A61K 38/22 (2006.01); A61K 38/26 (2006.01); A61K 38/27 (2006.01); A61K 9/00 (2006.01); A61K 9/50 (2006.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); A61K 9/0024 (2013.01); A61K 9/5036 (2013.01); A61K 35/12 (2013.01); A61K 38/10 (2013.01); A61K 38/105 (2013.01); A61K 38/1825 (2013.01); A61K 38/1866 (2013.01); A61K 38/22 (2013.01); A61K 38/2207 (2013.01); A61K 38/2264 (2013.01); A61K 38/26 (2013.01); A61K 38/27 (2013.01); A61K 47/6901 (2017.08); C12N 15/09 (2013.01); A01K 2207/12 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0393 (2013.01); C12N 2800/107 (2013.01); C12N 2800/60 (2013.01); C12N 2830/002 (2013.01);
Abstract

The invention relates to vectors and mammalian cells in a system useful for switching on or switching off gene expression in response to fatty acids, and a method of treating diet-induced obesity. In particular, a synthetic intracellular lipid-sensing receptor was constructed that constantly monitors blood fatty acid levels, processes diet-associated hyperlipidemia and coordinates reversible and adjustable expression of the anorectic peptide hormone pramlintide to reduce dietary intake, blood fat levels and body weight.

Find Patent Forward Citations

Rossger, Katrin. (2019). Designer circuit controlling diet-induced obesity (U.S. Patent No. 10415054). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10415054

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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