The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2019
Filed:
Sep. 14, 2017
Applicant:
Ajinomoto Co., Inc., Tokyo, JP;
Inventors:
Assignee:
AJINOMOTO CO., INC., Tokyo, JP;
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/04 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01); C12N 15/113 (2010.01); C12N 15/11 (2006.01); C07H 21/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C07D 413/04 (2013.01); C07D 487/04 (2013.01); C07D 519/00 (2013.01); C12N 15/111 (2013.01); C07H 21/00 (2013.01); C12N 2310/11 (2013.01); C12N 2310/3233 (2013.01); C12N 2330/30 (2013.01); Y02P 20/55 (2015.11);
Abstract
Using a morpholino nucleotide wherein 5'-hydroxy group or a hydroxy group present on the substituent of the 5′-hydroxy group is protected by a protecting group having an alkyl group having not less than 10 and not more than 300 carbon atoms and/or an alkenyl group having not less than 10 and not more than 300 carbon atoms as a starting material, a method capable of efficiently producing the morpholino oligonucleotide in a high yield by a liquid phase synthesis can be provided.