The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 17, 2019

Filed:

Nov. 28, 2018
Applicant:

Academia Sinica, Taipei, TW;

Inventors:

An-Suei Yang, Emeryville, CA (US);

Jhih-Wei Jian, Taipei, TW;

Hong-Sen Chen, Taipei, TW;

Yi-Kai Chiu, Taipei, TW;

Hung-Pin Peng, Taipei, TW;

Chao-Ping Tung, Taipei, TW;

Chung-Ming Yu, Taipei, TW;

Wei-Ying Kuo, Taipei, TW;

Hung-Ju Hsu, Taipei, TW;

Assignee:

Academia Sinica, Taipei, TW;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C40B 40/02 (2006.01); C07K 16/00 (2006.01); C07K 16/32 (2006.01); C07K 16/30 (2006.01); C07K 16/22 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1037 (2013.01); C07K 16/005 (2013.01); C07K 16/22 (2013.01); C07K 16/2827 (2013.01); C07K 16/30 (2013.01); C07K 16/32 (2013.01); C40B 40/02 (2013.01); C07K 2317/33 (2013.01); C07K 2317/622 (2013.01); C07K 2317/92 (2013.01);
Abstract

Disclosed herein is a phage-displayed single-chain variable fragment (scFv) library, which comprises a plurality of phage-displayed scFvs characterized in having a specific CS combination and a specific sequence in each CDR. The present scFv library is useful in efficiently producing different antibodies with binding affinity to different antigens. Accordingly, the present disclosure provides a potential means to generate different antigen-specific antibodies promptly in accordance with the need in experimental researches and/or clinical applications.


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