The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2019
Filed:
May. 07, 2016
H. Lee Moffitt Cancer Center and Research Institute, Inc., Tampa, FL (US);
The Wistar Institute of Anatomy and Biology, Philadelphia, PA (US);
Frederick L. Locke, Lutz, FL (US);
Dario Altieri, Philadelphia, PA (US);
Scott Antonia, Land O'Lakes, FL (US);
Claudio Anasetti, Saint Petersburg, FL (US);
Dmitry Gabrilovich, Villanova, PA (US);
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC., Tampa, FL (US);
THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY, Philadelphia, PA (US);
Abstract
The invention concerns a variant (double mutant form) of the survivin polypeptide; nucleic acid molecules encoding the survivin variant; antigen presenting cells (APCs) such as dendritic cells, or APC precursors, comprising the variant survivin polypeptide or encoding nucleic acid sequence; and methods for treating a malignancy, such as myeloma, or for inducing an immune response, utilizing a variant survivin polypeptide, nucleic acid molecule, or APC.