The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 17, 2019

Filed:

Aug. 10, 2017
Applicants:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Jared N. Cumming, Garwood, NJ (US);

Kevin D. Dykstra, West Milford, NJ (US);

Alan Hruza, Hackettstown, NJ (US);

Derun LI, Brighton, MA (US);

Hong Liu, Hillsborough, NJ (US);

Haiqun Tang, Belle Mead, NJ (US);

Brandon M. Taoka, Hoboken, NJ (US);

Andreas Verras, New York, NY (US);

Shawn P. Walsh, Bridgewater, NJ (US);

Wen-lian Wu, Green Brook, NJ (US);

Inventors:

Jared N. Cumming, Garwood, NJ (US);

Kevin D. Dykstra, West Milford, NJ (US);

Alan Hruza, Hackettstown, NJ (US);

Derun Li, Brighton, MA (US);

Hong Liu, Hillsborough, NJ (US);

Haiqun Tang, Belle Mead, NJ (US);

Brandon M. Taoka, Hoboken, NJ (US);

Andreas Verras, New York, NY (US);

Shawn P. Walsh, Bridgewater, NJ (US);

Wen-Lian Wu, Green Brook, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 519/00 (2006.01); A61P 3/10 (2006.01); C07D 498/04 (2006.01); C07D 513/04 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 3/10 (2018.01); C07D 471/04 (2013.01); C07D 498/04 (2013.01); C07D 513/04 (2013.01); C07D 519/00 (2013.01);
Abstract

Described herein are compounds of Formula (I) or a pharmaceutically acceptable salt thereof. The compounds of Formula I act as Cyp8b1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for diabetes and cardiovascular disease.


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