The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 17, 2019

Filed:

Jan. 29, 2018
Applicant:

Takeda Pharmaceutical Company Limited, Osaka-shi, Osaka, JP;

Inventors:

Shigemitsu Matsumoto, Kanagawa, JP;

Yasushi Hattori, Kanagawa, JP;

Masashi Toyofuku, Kanagawa, JP;

Shinji Morimoto, Kanagawa, JP;

Masaki Daini, Kanagawa, JP;

Takuto Kojima, Kanagawa, JP;

Tomohiro Kaku, Kanagawa, JP;

Mitsuhiro Ito, Kanagawa, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/14 (2006.01); C07D 417/12 (2006.01); C07D 409/12 (2006.01); C07D 307/79 (2006.01); C07D 407/12 (2006.01); C07D 213/82 (2006.01); C07D 333/38 (2006.01); C07D 413/14 (2006.01); C07D 231/14 (2006.01); C07D 333/40 (2006.01); C07D 285/08 (2006.01); C07D 231/12 (2006.01); C07D 277/56 (2006.01); C07D 409/14 (2006.01); C07D 413/12 (2006.01); C07D 307/81 (2006.01); C07D 285/135 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); C07D 213/82 (2013.01); C07D 231/12 (2013.01); C07D 231/14 (2013.01); C07D 277/56 (2013.01); C07D 285/08 (2013.01); C07D 285/135 (2013.01); C07D 307/79 (2013.01); C07D 307/81 (2013.01); C07D 333/38 (2013.01); C07D 333/40 (2013.01); C07D 407/12 (2013.01); C07D 409/12 (2013.01); C07D 409/14 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01);
Abstract

The present invention provides a compound having a lysine-specific demethylase-1 inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for schizophrenia, developmental disorders, particularly diseases having intellectual disability (e.g., autistic spectrum disorders, Rett syndrome, Down's syndrome, Kabuki syndrome, fragile X syndrome, Kleefstra syndrome, neurofibromatosis type 1, Noonan syndrome, tuberous sclerosis), neurodegenerative diseases (e.g., Alzheimer's disease, Parkinson's disease, spinocerebellar degeneration (e.g., dentatorubural pallidoluysian atrophy) and Huntington's disease), epilepsy (e.g., Dravet syndrome) or drug dependence, and the like. A compound represented by the formula wherein each symbol is as defined in the present specification, or a salt thereof.


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