The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2019
Filed:
Sep. 28, 2018
Applicant:
Kangwon National University, University Industry Cooperation Foundation, Chuncheon, Gangwon Province, KR;
Inventors:
Phil Ho Lee, Chuncheon-si, KR;
Koo Yeon Lee, Chuncheon-si, KR;
Yonghyeon Baek, Chuncheon-si, KR;
Kyusik Um, Chuncheon-si, KR;
Byeong Su Kim, Chuncheon-si, KR;
Assignee:
Kangwon National University Industry Cooperation Foundation, Gangwon-do, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 263/26 (2006.01); C07D 205/08 (2006.01); B01J 31/38 (2006.01); B01J 31/22 (2006.01);
U.S. Cl.
CPC ...
C07D 263/26 (2013.01); B01J 31/2278 (2013.01); B01J 31/38 (2013.01); C07D 205/08 (2013.01); B01J 2231/543 (2013.01); C07B 2200/07 (2013.01);
Abstract
Disclosed is a method of preparing ezetimibe, including cross-metathesis using a Grubbs 2catalyst and deprotection using a Pearlman's catalyst, and an intermediate thereof. The method of preparing ezetimibe is useful as an efficient ezetimibe synthesis technique in pharmaceutical fields using ezetimibe as a raw material.