The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 17, 2019

Filed:

Mar. 16, 2018
Applicant:

Aldeyra Therapeutics, Inc., Lexington, MA (US);

Inventors:

Amanda Buist, Glasgow, GB;

Eden Fucci, Arlington, MA (US);

Stephen G. Machatha, Burlington, MA (US);

Osama Suleiman, Cambridge, GB;

Kate Wittering, Hampshire, GB;

Assignee:

Aldeyra Therapeutics, Inc., Lexington, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/38 (2006.01); A61K 31/47 (2006.01); C07C 309/04 (2006.01); C07C 55/07 (2006.01); C07C 309/25 (2006.01); C07C 59/255 (2006.01); C07C 309/29 (2006.01); C07C 309/20 (2006.01); C07C 309/30 (2006.01);
U.S. Cl.
CPC ...
C07D 215/38 (2013.01); A61K 31/47 (2013.01); C07C 55/07 (2013.01); C07C 59/255 (2013.01); C07C 309/04 (2013.01); C07C 309/20 (2013.01); C07C 309/25 (2013.01); C07C 309/29 (2013.01); C07C 309/30 (2013.01); C07B 2200/13 (2013.01); C07C 2602/42 (2017.05);
Abstract

The present invention provides freebase and salt forms, and compositions and methods thereof, useful for treating various conditions, in which aldehyde toxicity is implicated in the pathogenesis, by the administration of small molecule therapeutics acting as a scavenger for toxic aldehydes.


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