The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 17, 2019

Filed:

Sep. 26, 2017
Applicant:

Cancer Research Technology Limited, London, GB;

Inventors:

Bernard Thomas Golding, Newcastle upon Tyne, GB;

Christiane Riedinger, Cambridge, GB;

Roger John Griffin, Lancaster Park, GB;

Ian Robert Hardcastle, Hexham, GB;

Eric Valeur, Vieux-Ferrette, FR;

Anna Frances Watson, Cambridge, GB;

Martin Noble, Newcastle upon Tyne, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/49 (2006.01); C07D 209/48 (2006.01); C07D 401/06 (2006.01); C07D 403/06 (2006.01); A61K 31/4035 (2006.01); A61K 31/4402 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 209/49 (2013.01); A61K 31/4035 (2013.01); A61K 31/4402 (2013.01); A61K 45/06 (2013.01); C07D 209/48 (2013.01); C07D 401/06 (2013.01); C07D 403/06 (2013.01);
Abstract

A compound of formula (I) or a compound of formula (II) or pharmaceutically acceptable salts thereof, wherein R1-R7 and X are as defined in the description, and the use of these compounds in therapy, in particular in treating cancer or as an inhibitor of the interaction of the MDM2 protein with p53.


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