The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 17, 2019

Filed:

Feb. 22, 2017
Applicants:

Baxalta Incorporated, Bannockburn, IL (US);

Baxalta Gmbh, Zug, CH;

Inventors:

Alexandra Nathalie Kopic, Vienna, AT;

Werner Höllriegl, Altenmarkt/Triesting, AT;

Barbara Plaimauer, Vienna, AT;

Hanspeter Rottensteiner, Vienna, AT;

Eva-Maria Muchitsch, Vienna, AT;

Assignees:

Baxalta Incorporated, Bannockburn, IL (US);

Baxalta GmbH, Zug, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01); C12N 9/64 (2006.01); A61K 9/00 (2006.01); A61K 9/19 (2006.01);
U.S. Cl.
CPC ...
A61K 38/4886 (2013.01); A61K 9/0019 (2013.01); A61K 9/19 (2013.01); C12N 9/6489 (2013.01); C12Y 304/24087 (2013.01);
Abstract

This invention relates to methods of subcutaneous administration of ADAMTS13 formulations to a treat a disease or condition associated with ADAMTS13 and VWF dysfunction. Furthermore, evidence of the unexpectedly high bioavailability of ADAMTS13 formulations administered subcutaneously is provided herein.


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