The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2019
Filed:
Dec. 12, 2018
Applicant:
The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, AU;
Inventors:
Esther Bandala Sanchez, Melbourne, AU;
James Dromey, Melbourne, AU;
Leonard Charles Harrison, Melbourne, AU;
Yuxia Zhang, Melbourne, AU;
Assignee:
The Walter and Eliza Hall Institute of Medical Research, Parkville, AU;
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); C07K 14/705 (2006.01); A61K 38/10 (2006.01); C12N 5/0783 (2010.01); G01N 33/50 (2006.01); C12Q 1/6883 (2018.01); C07K 16/18 (2006.01); A61K 47/68 (2017.01); G01N 33/68 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/177 (2013.01); A61K 47/68 (2017.08); C07K 14/70592 (2013.01); C07K 16/18 (2013.01); C12N 5/0637 (2013.01); C12Q 1/6883 (2013.01); G01N 33/505 (2013.01); G01N 33/6872 (2013.01); A61K 38/10 (2013.01); A61K 48/00 (2013.01); C07K 2319/30 (2013.01);
Abstract
The present disclosure relates to a soluble CD52 glycoprotein and its use in treating diseases regulated by effector T-cells, for example autoimmune diseases such as type I diabetes. The present disclosure also relates to fusion proteins comprising the soluble glycoprotein, to cells expressing high levels of CD52, and to diagnostic methods based on the detection of CD52 expression levels in a subject.