The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 17, 2019
Filed:
Jul. 01, 2014
Korea Research Institute of Bioscience and Biotechnology, Daejeon, KR;
Kyung Seop Ahn, Daejeon, KR;
Sei Ryang Oh, Daejeon, KR;
Ok Kyoung Kwon, Daejeon, KR;
In Sik Shin, Daejeon, KR;
Hyung Won Ryu, Daejeon, KR;
Sang Woo Lee, Daejeon, KR;
Joong Ku Lee, Daejeon, KR;
Hyeong Kyu Lee, Daejeon, KR;
Sang Ho Choi, Daejeon, KR;
Doo Young Kim, Daejeon, KR;
Jung Hee Kim, Daejeon, KR;
Li Wan Yi, Kunming, CN;
Jin Hang, Kunming, CN;
Korea Research Institute of Bioscience and Biotechnology, Daejeon, KR;
Abstract
The present invention relates to a composition for preventing or treating asthma comprising aJ. Poiss. ex Franch extract or a fraction thereof. TheJ. Poiss. ex Franch extract or the fraction thereof according to the present invention does not exhibit toxicity, inhibits the generation of NO, IL-4, IL-5, and IL-13 and the generation of reactive oxygen species in the bronchial tubes, and has significantly induced the alleviation of airway hyperresponsiveness, inhibition of the infiltration of inflammatory cells into the bronchial tubes, and reduction of inflammatory cells in bronchoalveolar lavage fluid in an ovalbumin-induced asthma mouse model. In addition, theJ. Poiss. ex Franch extract or the fraction thereof according to the present invention effectively inhibits the secretion of immunoglobulins in serum, secretion of mucus in the bronchial tubes, and infiltration of inflammatory cells into lung tissue and thus can be usefully used as a safe preparation for preventing and treating asthma.