The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 17, 2019

Filed:

Aug. 15, 2013
Applicant:

National University of Singapore, Singapore, SG;

Inventors:

Chui Yee Fong, Singapore, SG;

Mahesh Choolani, Singapore, SG;

Arijit Biswas, Singapore, SG;

Tuan Ariffeen Bongso, Singapore, SG;

Seeram Ramakrishna, Singapore, SG;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/51 (2015.01); C12N 5/073 (2010.01); A61K 36/886 (2006.01); A61L 27/18 (2006.01); A61L 27/36 (2006.01); A61L 27/38 (2006.01); A61L 27/54 (2006.01); A61L 27/56 (2006.01); A61L 15/26 (2006.01); A61L 15/40 (2006.01); A61L 15/42 (2006.01); A61L 15/44 (2006.01);
U.S. Cl.
CPC ...
A61K 35/51 (2013.01); A61K 36/886 (2013.01); A61L 15/26 (2013.01); A61L 15/40 (2013.01); A61L 15/425 (2013.01); A61L 15/44 (2013.01); A61L 27/18 (2013.01); A61L 27/3637 (2013.01); A61L 27/3834 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); C12N 5/0605 (2013.01); A61L 2300/104 (2013.01); A61L 2300/30 (2013.01); A61L 2300/406 (2013.01); A61L 2300/418 (2013.01); A61L 2300/64 (2013.01); A61L 2400/12 (2013.01);
Abstract

The invention is directed to a method of treating a wound (e.g., to suppress scar formation) in an individual in need thereof comprising contacting the wound with an effective amount of a composition comprising (i) Wharton's jelly stem cells (WJSCs), (ii) a cell culture medium that has been conditioned with WJSCs, (iii) a lysate of WJSCs, (iv) a cell culture medium that has been conditioned with WJSCs exposed to apoptotic skin cells and keloid cells, or (v) a combination thereof. The invention is directed to a medical dressing (e.g., pharmaceutical compositions) comprising Wharton's jelly stem cells (WJSCs), a cell culture medium that has been conditioned with WJSCs, a lysate of WJSCs, a cell culture medium that has been conditioned with WJSCs exposed to apoptotic skin cells and keloid cells, or a combination thereof.


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