The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 17, 2019

Filed:

Jun. 22, 2017
Applicant:

Crystalgenomics, Inc., Gyeonggi-do, KR;

Inventors:

Byung-Ha Kim, Seoul, KR;

Sik II Ahn, Gyeonggi-do, KR;

Jae-Yeon Park, Seoul, KR;

Tae Ryong Kim, Seoul, KR;

Joong Myung Cho, Seoul, KR;

Seonggu Ro, Seoul, KR;

Assignee:

CRYSTALGENOMICS, INC., Gyeonggi-do, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/341 (2006.01); A61K 9/48 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
A61K 31/341 (2013.01); A61K 9/2009 (2013.01); A61K 9/2013 (2013.01); A61K 9/2018 (2013.01); A61K 9/2027 (2013.01); A61K 9/2054 (2013.01); A61K 9/2059 (2013.01); A61K 9/48 (2013.01); A61K 9/485 (2013.01); A61K 9/4858 (2013.01); A61K 9/4866 (2013.01);
Abstract

The present invention relates to a pharmaceutical composition including (i) as a major ingredient, a novel 5-{4-(Aminosulfonyl)phenyl}-2,2-dimethyl-4-(3-fluorophenyl)-3(2H)-furanone compound (Formula 1) or a pharmaceutically acceptable salt thereof, which has a crystalline form A or G, or a mixed form thereof and has a 50% volume particle diameter (d) of 3 μm to 9 μm and a 90% volume particle diameter (d) of 10 μm to 50 μm, (ii) a pharmaceutically acceptable diluent, and (iii) a pharmaceutically acceptable lubricant. The pharmaceutical composition of the present invention has the advantages of good stability, high dissolution rate, improved content uniformity, and excellent pharmacokinetic properties. Due to these advantages, as a non-steroidal anti-inflammatory drug, the pharmaceutical composition of the present invention may be effective in treating inflammation or pain.


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