The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 17, 2019

Filed:

Jun. 27, 2013
Applicant:

University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Inventors:

Xucai Chen, Pittsburgh, PA (US);

Jianjun Wang, Pittsburgh, PA (US);

John J. Pacella, Pittsburgh, PA (US);

Flordeliza S. Villanueva, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 8/08 (2006.01); A61N 7/00 (2006.01); A61K 41/00 (2006.01); A61K 49/22 (2006.01); A61M 37/00 (2006.01); A61N 7/02 (2006.01); A61M 5/00 (2006.01); A61M 31/00 (2006.01); A61B 17/00 (2006.01); A61B 90/00 (2016.01);
U.S. Cl.
CPC ...
A61B 8/481 (2013.01); A61K 41/0028 (2013.01); A61K 49/223 (2013.01); A61M 5/007 (2013.01); A61M 37/0092 (2013.01); A61N 7/00 (2013.01); A61N 7/02 (2013.01); A61B 8/5261 (2013.01); A61B 2017/00181 (2013.01); A61B 2017/00194 (2013.01); A61B 2090/373 (2016.02); A61B 2090/378 (2016.02); A61M 31/005 (2013.01); A61N 2007/0039 (2013.01); A61N 2007/0052 (2013.01);
Abstract

Various methods of performing ultrasound contrast assisted therapy are provided. One such method includes delivering a plurality of microbubble-based ultrasound contrast agents to a target area and disrupting the microbubble-based ultrasound contrast agents by delivering tone bursts of ultrasound to the target area. The oscillation of the microbubble-based ultrasound contrast agents can be achieved by delivering ultrasound tone bursts of greater than 5 acoustic cycles with a pulse repetition frequency of between 0.01 and 20 Hz, with pressure greater than 0.3 MPa.


Find Patent Forward Citations

Loading…