The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2019
Filed:
Nov. 15, 2016
Obi Pharma, Inc., Taipei, TW;
Jian-Xin Duan, South San Francisco, CA (US);
Yeyu Cao, South San Francisco, CA (US);
Xiaohong Cai, South San Francisco, CA (US);
Hailong Jiao, South San Francisco, CA (US);
Jing Yuan Ma, South San Francisco, CA (US);
Mark Matteucci, South San Francisco, CA (US);
OBI PHARMA, INC., Taipei, TW;
Abstract
Provided herein are optically active compounds of the formulae (ii); and (III) and pharmaceutical compositions thereof. Also provided herein are processes of making these compounds and resolving the racemic mixture or the enrichment of same with in one of its enantiomers to provide (R)- and (S)-1-(3-(3-N,N-dimethylaminocarbonyl)phenoxyl-4-nitrophenyl)-1-ethyl-N,N'-bis(ethylene)phosphoramidate, and methods of treating cancer comprising administering such compounds.