The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 10, 2019

Filed:

Sep. 20, 2017
Applicant:

Somalogic, Inc., Boulder, CO (US);

Inventors:

Urs Ochsner, Boulder, CO (US);

David G. Sterling, Boulder, CO (US);

Nebojsa Janjic, Boulder, CO (US);

Assignee:

SomaLogic, Inc., Boulder, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/04 (2006.01); A61K 39/02 (2006.01); A61K 39/00 (2006.01); G01N 33/68 (2006.01); C12Q 1/6883 (2018.01); G01N 33/569 (2006.01); A61K 31/496 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); A61K 31/496 (2013.01); C12Q 1/6883 (2013.01); G01N 33/5695 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/158 (2013.01); G01N 2570/00 (2013.01); G01N 2800/52 (2013.01); G01N 2800/60 (2013.01);
Abstract

The present application includes biomarkers, methods, devices, reagents, systems, and kits for the detection, treatment and diagnosis of tuberculosis (TB). In one aspect, the present application includes the identification of biomarkers that can be used alone or in various combinations for the detection of TB, including those set forth in Tables 1, 2, 4, 5, and 8 to 12. In another aspect, the application provides biomarkers that can be used alone or in various combinations to diagnose or prognose TB or follow treatment response. In another aspect, methods are provided for diagnosing TB in an individual, where the methods include detecting, in a biological sample from an individual, at least one biomarker value corresponding to at least one biomarker selected from the group of biomarkers provided in Tables 1, 2, 4, 5, and 8 to 12, wherein the individual is classified as having TB, or the likelihood of the individual having TB is determined, based on the at least one biomarker value.


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