The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2019
Filed:
Aug. 03, 2015
Applicant:
Singapore Volition Pte. Limited, Singapore, SG;
Inventors:
Lindsay Jane Bawden, Abingdon, GB;
Elisabeth Ann Bone, Abingdon, GB;
Alan Hastings Drummond, Abingdon, GB;
Lindsey Ann Needham, Abingdon, GB;
Assignee:
SINGAPORE VOLITION PTE. LIMITED, Singapore, SG;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/564 (2006.01); G01N 33/574 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/564 (2013.01); G01N 33/57488 (2013.01); G01N 33/6875 (2013.01); G01N 2800/24 (2013.01); G01N 2800/7028 (2013.01);
Abstract
This invention relates to the diagnosis of disease conditions, such as cancer and autoimmune disease, by the analysis of cell-free nucleosomes in samples from individuals. Methods of the invention may include contacting cell-free nucleosomes from a biological fluid sample obtained from the individual with an antibody that binds specifically with a modified histone protein. Binding of the antibody to the nucleosomes is indicative that the individual has the disease condition.