The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2019
Filed:
Apr. 17, 2015
Medizinische Hochschule Hannover, Hannover, DE;
Timm Fiebig, Hannover, DE;
Tim Keys, Uster, CH;
Friedrich Freiberger, Wunstorf, DE;
Angela Romanow, Laatzen, DE;
Andrea Bethe, Hildesheim/Itzum, DE;
Monika Berger, Sehnde, DE;
Rita Gerardy-Schahn, Hiddenhausen, DE;
Medizinische Hochschule Hannover, Hannover, DE;
Abstract
The present invention relates to in vitro methods for producingcapsular polysaccharides which have a defined length. The present invention also relates to compositions comprising at least one capsule polymerase, at least one donor carbohydrate and at least one acceptor carbohydrate, wherein the ratio of donor carbohydrate to acceptor carbohydrate is a ratio from 10:1 to 400:1. Moreover, the present invention provides truncated versions of the capsule polymerases ofserogroups A and X. Also provided herein are pharmaceuticals, in particular vaccines, comprising the synthetic capsular polysaccharides ofwhich have a defined length. Furthermore, the invention provides for methods for the production of said vaccines.