The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2019
Filed:
May. 23, 2016
Applicant:
Daiichi Sankyo Company, Limited, Chuo-ku, Tokyo, JP;
Inventors:
Daisuke Nishimiya, Tokyo, JP;
Tatsuya Inoue, Tokyo, JP;
Assignee:
Daiichi Sankyo Company, Limited, Tokyo, JP;
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/85 (2006.01); C07K 16/00 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); C07K 16/00 (2013.01); C12P 21/00 (2013.01); C07K 2317/14 (2013.01); C07K 2317/24 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C12N 2800/107 (2013.01); C12N 2830/46 (2013.01);
Abstract
Disclosed is a method for stably achieving high expression of a foreign gene in mammalian cells using a novel DNA element. More specifically disclosed is a DNA element which enhances the activation of transcription by changing the chromatin structure around a gene locus into which a foreign gene expression unit has been introduced.