The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2019
Filed:
Jul. 01, 2016
Applicant:
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Inventors:
Ulrich Brinkmann, Weilheim, DE;
Guy Georges, Habach, DE;
Eike Hoffmann, Herrsching a. Ammersee, DE;
Georg Tiefenthaler, Sindelsdorf, DE;
Ekkehard Moessner, Kreuzlingen, CH;
Stefan Dengl, Munich, DE;
Achim Gaertner, Bad Heilbrunn, DE;
Assignee:
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/44 (2006.01); A61K 47/68 (2017.01); A61K 39/00 (2006.01); C07K 7/08 (2006.01); C07K 16/26 (2006.01);
U.S. Cl.
CPC ...
C07K 16/44 (2013.01); A61K 47/6811 (2017.08); A61K 47/6829 (2017.08); A61K 47/6879 (2017.08); C07K 7/08 (2013.01); C07K 16/26 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/34 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/624 (2013.01); C07K 2317/94 (2013.01); C07K 2319/31 (2013.01); C07K 2319/70 (2013.01); C07K 2319/73 (2013.01); C07K 2319/75 (2013.01);
Abstract
Herein is reported a conjugate comprising a helicar motif amino acid sequence containing compound and an antibody that specifically binds to the helicar motif amino acid sequence characterized by a covalent bond between the helicar motif amino acid sequence containing compound and an amino acid residue in the CDR2 of the anti-helicar antibody, whereby the CDR2 is determined according to Kabat.