The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 10, 2019
Filed:
Jul. 30, 2014
Applicant:
Blueprint Medicines Corporation, Cambridge, MA (US);
Inventors:
Nicolas Stransky, Charlestown, MA (US);
Ethan G. Cerami, Winchester, MA (US);
Christoph Lengauer, Cambridge, MA (US);
Assignee:
Blueprint Medicines Corporation, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); C12Q 1/6886 (2018.01); C12Q 1/48 (2006.01); G01N 33/574 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); C07K 16/2863 (2013.01); C07K 16/30 (2013.01); C12N 15/1137 (2013.01); C12Q 1/485 (2013.01); C12Q 1/6886 (2013.01); G01N 33/57484 (2013.01); G01N 33/57492 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01); C12N 2320/30 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01); G01N 2333/91205 (2013.01); G01N 2500/04 (2013.01);
Abstract
The invention provides to NTRK ('Neurotrophic Tyrosine Receptor Kinase) gene fusions, NTRK, fusion proteins, and fragments of those genes and polypeptides. The invention further provides methods of diagnosing and treating diseases or disorders associated with NTRK fusions, such as conditions mediated by aberrant NTRK expression or activity, or overexpression of NTRK.