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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10407466 B1

PDFFull Text
Date of Patent:
Sep. 10, 2019

Filed:

Jan. 06, 2017

Methods of selecting compstatin mimetics

Applicant:

Apellis Pharmaceuticals, Inc., Crestwood, KY (US);

Inventors:

Pascal Deschatelets, Prospect, KY (US);

Paul Olson, St. Louis, MO (US);

Cedric Francois, Prospect, KY (US);

Assignee:

Apellis Pharmaceuticals, Inc., Crestwood, KY (US);

Attorneys:

Choate, Hall & Stewart LLP

Brenda Herschbach Jarrell

Rolando Medina

Primary Examiner:

Gyan Chandra

Int. Cl.
CPC ...
A61K 38/08 (2019.01); C07K 7/08 (2006.01); A61K 9/00 (2006.01); A61K 31/00 (2006.01); A61K 38/10 (2006.01); A61K 38/12 (2006.01); A61K 38/17 (2006.01); A61K 31/7105 (2006.01); A61K 39/395 (2006.01); A61K 49/00 (2006.01); C07K 16/28 (2006.01); G01N 33/68 (2006.01); A61F 9/00 (2006.01); A61K 39/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61K 9/0019 (2013.01); A61K 9/0048 (2013.01); A61K 9/0051 (2013.01); A61K 31/00 (2013.01); A61K 31/7105 (2013.01); A61K 38/08 (2013.01); A61K 38/10 (2013.01); A61K 38/12 (2013.01); A61K 38/17 (2013.01); A61K 39/3955 (2013.01); A61K 49/0008 (2013.01); C07K 16/28 (2013.01); G01N 33/6872 (2013.01); A61F 9/0008 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2319/01 (2013.01); G01N 2333/4704 (2013.01); G01N 2500/04 (2013.01); G01N 2500/20 (2013.01);
Abstract

The present invention features the use of compstatin and complement inhibiting analogs thereof for treating and/or preventing age related macular degeneration and other conditions involving macular degeneration, choroidal neovascularization, and/or retinal neovascularization. The invention also provides compositions comprising compstatin or a complement inhibiting analog thereof and a second therapeutic agent. The invention also provides compositions comprising compstatin or a complement inhibiting analog thereof and a gel-forming material, e.g., soluble collagen, and methods of administering the compositions.

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