The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 10, 2019

Filed:

Jun. 03, 2016
Applicant:

Kyowa Hakko Bio Co., Ltd., Tokyo, JP;

Inventors:

Maya Iguchi, Tokyo, JP;

Kazunari Fukumoto, Tokyo, JP;

Hiroshi Nagano, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 5/037 (2006.01); C07K 1/02 (2006.01); C07K 1/30 (2006.01); C07K 5/02 (2006.01); C07K 5/06 (2006.01); C07K 5/08 (2006.01);
U.S. Cl.
CPC ...
C07K 1/306 (2013.01); C07K 1/02 (2013.01); C07K 5/0215 (2013.01); C07K 5/06 (2013.01); C07K 5/08 (2013.01);
Abstract

The invention provides a method of efficiently and stably producing α-form crystal of reduced glutathione, and a preservation method thereof. According to the invention, development of β-form crystal and/or transition to β-form crystal of reduced glutathione are suppressed by the coexistence of at least one kind of compound selected from the group of aliphatic amino acid, sulfur-containing amino acid, aromatic amino acid, an analogous compound and dipeptide, as a habit modifier, during production and preservation of an aqueous solution or α-form crystal of reduced glutathione.


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